In total 14 teachers, two head teachers and support staff have all left their jobs at Our Lady of Lourdes Catholic Primary School.
The final seven members of staff will leave today as the summer term ends and many teachers have previously been signed off for stress.
Union representatives claim that leadership at the school led to the mass walk-out.
The National Union of Teachers (NUT) have blamed high work loads for the walkout, with one insider saying it made their job ‘impossible’.
However, governors at the school in Kingswood, Bristol, are trying to reassure people that there will be a new set of teaching staff in place for the new academic year in September.
After its last Ofsted inspection in November 2013 the school was given a good rating, but in 2016 SATs results were below the standard set by the Department for Education.
Fewer than one in four children achieved the required standard for reading, writing and mathematics.
South Gloucestershire Council, which runs the school, told its leaders it needed to improve.
Parents were told the level of staff sickness was ‘out of control’ by chair of governors Lisa Paniccia-Brown.
Headteacher Clare Murray left and was replaced by Louisa Wilson who was appointed as ‘executive’ head.