Hallmarks Of Cancer: Failure To Respond To 'STOP' Signals


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The division of normal cells is restricted by signals from other cells. Cells will stop dividing when they are in contact with neighboring cells. This cell:cell contacts send signals into the dividing cells that cause them to stop dividing. An alternative mechanism to stop cell division is called differentiation. 

This is the process by which a cell shows different charactersitics because it has a certain function . An example of this would be the maturation of a stem cell to a fully mature colon epithelial cell. 

The maturation process involves the cells ability to express certain genes, which results in differential properties for the cells.

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